在核医学中，规定放射性碘治疗以治疗甲状腺功能亢进等疾病。规定剂量的计算在甲状腺体积上取决于其他因素。目前使用传统的2D超声成像估计这一点。但是，这种模态本质上是依赖的，导致体积估计的高变异性。为了提高再现性和一致性，我们用甲状腺体积的自动机器人超声扫描唯一地结合了基于神经网络的分割。通过使用具有连接超声探头的6 DOF机器人臂实现机器人采集。其运动基于每个甲状腺叶的在线分割和美国图像的外观。在后处理期间，将美国图像分段以获得体积估计。在一种消融研究中，与机器人在体积精度方面执行的与机器人执行的天真线性运动相比，我们证明了机器人臂运动的运动引导算法的优越性。在对幻影的用户研究中，我们将传统的2D超声测量与机器人系统进行了比较。与地面真理相比，超声专家用户的平均体积测量误差可能会从20.85 +/- 16.10％显着降低到仅8.23 +/- 3.10％。在非专家用户中观察到这种趋势，其中测量了与机器人系统的平均误差改善，以高达85美元的价格，这显然显示了机器人支持的优势。

The release of ChatGPT, a language model capable of generating text that appears human-like and authentic, has gained significant attention beyond the research community. We expect that the convincing performance of ChatGPT incentivizes users to apply it to a variety of downstream tasks, including prompting the model to simplify their own medical reports. To investigate this phenomenon, we conducted an exploratory case study. In a questionnaire, we asked 15 radiologists to assess the quality of radiology reports simplified by ChatGPT. Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient. Nevertheless, instances of incorrect statements, missed key medical findings, and potentially harmful passages were reported. While further studies are needed, the initial insights of this study indicate a great potential in using large language models like ChatGPT to improve patient-centered care in radiology and other medical domains.

The SINDy algorithm has been successfully used to identify the governing equations of dynamical systems from time series data. In this paper, we argue that this makes SINDy a potentially useful tool for causal discovery and that existing tools for causal discovery can be used to dramatically improve the performance of SINDy as tool for robust sparse modeling and system identification. We then demonstrate empirically that augmenting the SINDy algorithm with tools from causal discovery can provides engineers with a tool for learning causally robust governing equations.

Markowitz mean-variance portfolios with sample mean and covariance as input parameters feature numerous issues in practice. They perform poorly out of sample due to estimation error, they experience extreme weights together with high sensitivity to change in input parameters. The heavy-tail characteristics of financial time series are in fact the cause for these erratic fluctuations of weights that consequently create substantial transaction costs. In robustifying the weights we present a toolbox for stabilizing costs and weights for global minimum Markowitz portfolios. Utilizing a projected gradient descent (PGD) technique, we avoid the estimation and inversion of the covariance operator as a whole and concentrate on robust estimation of the gradient descent increment. Using modern tools of robust statistics we construct a computationally efficient estimator with almost Gaussian properties based on median-of-means uniformly over weights. This robustified Markowitz approach is confirmed by empirical studies on equity markets. We demonstrate that robustified portfolios reach the lowest turnover compared to shrinkage-based and constrained portfolios while preserving or slightly improving out-of-sample performance.

A critical step in sharing semantic content online is to map the structural data source to a public domain ontology. This problem is denoted as the Relational-To-Ontology Mapping Problem (Rel2Onto). A huge effort and expertise are required for manually modeling the semantics of data. Therefore, an automatic approach for learning the semantics of a data source is desirable. Most of the existing work studies the semantic annotation of source attributes. However, although critical, the research for automatically inferring the relationships between attributes is very limited. In this paper, we propose a novel method for semantically annotating structured data sources using machine learning, graph matching and modified frequent subgraph mining to amend the candidate model. In our work, Knowledge graph is used as prior knowledge. Our evaluation shows that our approach outperforms two state-of-the-art solutions in tricky cases where only a few semantic models are known.

Using robots in educational contexts has already shown to be beneficial for a student's learning and social behaviour. For levitating them to the next level of providing more effective and human-like tutoring, the ability to adapt to the user and to express proactivity is fundamental. By acting proactively, intelligent robotic tutors anticipate possible situations where problems for the student may arise and act in advance for preventing negative outcomes. Still, the decisions of when and how to behave proactively are open questions. Therefore, this paper deals with the investigation of how the student's cognitive-affective states can be used by a robotic tutor for triggering proactive tutoring dialogue. In doing so, it is aimed to improve the learning experience. For this reason, a concept learning task scenario was observed where a robotic assistant proactively helped when negative user states were detected. In a learning task, the user's states of frustration and confusion were deemed to have negative effects on the outcome of the task and were used to trigger proactive behaviour. In an empirical user study with 40 undergraduate and doctoral students, we studied whether the initiation of proactive behaviour after the detection of signs of confusion and frustration improves the student's concentration and trust in the agent. Additionally, we investigated which level of proactive dialogue is useful for promoting the student's concentration and trust. The results show that high proactive behaviour harms trust, especially when triggered during negative cognitive-affective states but contributes to keeping the student focused on the task when triggered in these states. Based on our study results, we further discuss future steps for improving the proactive assistance of robotic tutoring systems.

We present Mu$^{2}$SLAM, a multilingual sequence-to-sequence model pre-trained jointly on unlabeled speech, unlabeled text and supervised data spanning Automatic Speech Recognition (ASR), Automatic Speech Translation (AST) and Machine Translation (MT), in over 100 languages. By leveraging a quantized representation of speech as a target, Mu$^{2}$SLAM trains the speech-text models with a sequence-to-sequence masked denoising objective similar to T5 on the decoder and a masked language modeling (MLM) objective on the encoder, for both unlabeled speech and text, while utilizing the supervised tasks to improve cross-lingual and cross-modal representation alignment within the model. On CoVoST AST, Mu$^{2}$SLAM establishes a new state-of-the-art for models trained on public datasets, improving on xx-en translation over the previous best by 1.9 BLEU points and on en-xx translation by 1.1 BLEU points. On Voxpopuli ASR, our model matches the performance of an mSLAM model fine-tuned with an RNN-T decoder, despite using a relatively weaker sequence-to-sequence architecture. On text understanding tasks, our model improves by more than 6\% over mSLAM on XNLI, getting closer to the performance of mT5 models of comparable capacity on XNLI and TydiQA, paving the way towards a single model for all speech and text understanding tasks.

The application of Natural Language Processing (NLP) to specialized domains, such as the law, has recently received a surge of interest. As many legal services rely on processing and analyzing large collections of documents, automating such tasks with NLP tools emerges as a key challenge. Many popular language models, such as BERT or RoBERTa, are general-purpose models, which have limitations on processing specialized legal terminology and syntax. In addition, legal documents may contain specialized vocabulary from other domains, such as medical terminology in personal injury text. Here, we propose LegalRelectra, a legal-domain language model that is trained on mixed-domain legal and medical corpora. We show that our model improves over general-domain and single-domain medical and legal language models when processing mixed-domain (personal injury) text. Our training architecture implements the Electra framework, but utilizes Reformer instead of BERT for its generator and discriminator. We show that this improves the model's performance on processing long passages and results in better long-range text comprehension.

The polynomial kernels are widely used in machine learning and they are one of the default choices to develop kernel-based classification and regression models. However, they are rarely used and considered in numerical analysis due to their lack of strict positive definiteness. In particular they do not enjoy the usual property of unisolvency for arbitrary point sets, which is one of the key properties used to build kernel-based interpolation methods. This paper is devoted to establish some initial results for the study of these kernels, and their related interpolation algorithms, in the context of approximation theory. We will first prove necessary and sufficient conditions on point sets which guarantee the existence and uniqueness of an interpolant. We will then study the Reproducing Kernel Hilbert Spaces (or native spaces) of these kernels and their norms, and provide inclusion relations between spaces corresponding to different kernel parameters. With these spaces at hand, it will be further possible to derive generic error estimates which apply to sufficiently smooth functions, thus escaping the native space. Finally, we will show how to employ an efficient stable algorithm to these kernels to obtain accurate interpolants, and we will test them in some numerical experiment. After this analysis several computational and theoretical aspects remain open, and we will outline possible further research directions in a concluding section. This work builds some bridges between kernel and polynomial interpolation, two topics to which the authors, to different extents, have been introduced under the supervision or through the work of Stefano De Marchi. For this reason, they wish to dedicate this work to him in the occasion of his 60th birthday.

Human speech can be characterized by different components, including semantic content, speaker identity and prosodic information. Significant progress has been made in disentangling representations for semantic content and speaker identity in Automatic Speech Recognition (ASR) and speaker verification tasks respectively. However, it is still an open challenging research question to extract prosodic information because of the intrinsic association of different attributes, such as timbre and rhythm, and because of the need for unsupervised training schemes to achieve robust large-scale and speaker-independent ASR. The aim of this paper is to address the disentanglement of emotional prosody from speech based on unsupervised reconstruction. Specifically, we identify, design, implement and integrate three crucial components in our proposed speech reconstruction model Prosody2Vec: (1) a unit encoder that transforms speech signals into discrete units for semantic content, (2) a pretrained speaker verification model to generate speaker identity embeddings, and (3) a trainable prosody encoder to learn prosody representations. We first pretrain the Prosody2Vec representations on unlabelled emotional speech corpora, then fine-tune the model on specific datasets to perform Speech Emotion Recognition (SER) and Emotional Voice Conversion (EVC) tasks. Both objective and subjective evaluations on the EVC task suggest that Prosody2Vec effectively captures general prosodic features that can be smoothly transferred to other emotional speech. In addition, our SER experiments on the IEMOCAP dataset reveal that the prosody features learned by Prosody2Vec are complementary and beneficial for the performance of widely used speech pretraining models and surpass the state-of-the-art methods when combining Prosody2Vec with HuBERT representations. Some audio samples can be found on our demo website.